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Promising drug candidate offers new hope for rare eye infection – Acanthamoeba Keratitis

A drug candidate developed through collaborative research between UCL and Moorfields Eye Hospital is proving highly effective in treating Acanthamoeba keratitis (AK), a rare and sight-threatening eye infection. The drug, a low concentration of polihexanide (PHMB 0.08%), is being studied as part of a clinical trial in partnership with SIFI S.p.A. AK, a corneal infection, can cause extreme pain and light sensitivity, affecting contact lens wearers disproportionately. The trial, involving 127 individuals across Europe, showed an 87% medical cure rate for AK using the high-concentration polihexanide, a remarkable success. The drug is particularly advantageous when administered as monotherapy, and the research may lead to regulatory approvals for its use in Europe, the UK, and the US, offering hope to AK patients.

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According to Business Wire, global Healthcare Industry will be worth $12T by 2022. Healthcare is vast and highly fragmented with a mix of public and private players. It comprises patients and healthcare providers such as hospitals, pharmaceuticals, and related life sciences.

Digitisation and Post-Covid world are set to transform the healthcare industry in the coming decade. Our weekly business newsletter covers innovations and disruptions in the Healthcare industry with global coverage.

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